Fluticasone propionate

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

丙酸氟替卡松是一种高亲和力、选择性 GR（糖皮质激素受体）激动剂，源自用于治疗哮喘和过敏性鼻炎的氟替卡松。

Fluticasone propionate is a high affinity, selective GR (glucocorticoid receptor) agonist which is derived from fluticasone used to treat asthma and allergic rhinitis.(In Vitro):Fluticasone propionate inhibits TNFα-induced E-selectin expression, with an IC50 of 1 nM.

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Fluticasone 17-Propionate

Endocrinology/Hormones

Estrogen Receptor/ERR

ER| Mineralocorticoid Receptor| Glucocorticoid Receptor| Cytosolic PLA2

Inflammation/Immunology

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80474-14-2

500.57

C25H31F3O5S

>98% (HPLC)

Ethanol: 5 mg/mL (9.98 mM); DMSO: 100 mg/mL (199.77 mM)

CCC(O[C@]1(C(SCF)=O)[C@H](C)C[C@@H]2[C@]1(C)C[C@H](O)[C@@]3(F)[C@H]2C[C@H](F)C4=CC(C=C[C@@]43C)=O)=O

(6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-17-(((fluoromethyl)thio)carbonyl)-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl propionate

(-20℃)

With Ice Pack

≥ 2 years