Fluticasone propionate ( Fluticasone 17-Propionate )

产品货号. M16013 CAS No. 80474-14-2

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Fluticasone propionate
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Fluticasone propionate is a high affinity, selective GR (glucocorticoid receptor) agonist which is derived from fluticasone used to treat asthma and allergic rhinitis.
产品描述

Fluticasone propionate is a high affinity, selective GR (glucocorticoid receptor) agonist which is derived from fluticasone used to treat asthma and allergic rhinitis.
同义词

Fluticasone 17-Propionate
通路

Endocrinology/Hormones
靶点

Estrogen Receptor/ERR
受体

ER; Mineralocorticoid Receptor; Glucocorticoid Receptor; Cytosolic PLA2
研究领域

Inflammation/Immunology
适应症

——

CAS Number

80474-14-2
分子量

500.57
分子式

C25H31F3O5S
纯度

>98%(HPLC)
溶解度

Ethanol: 5 mg/mL (9.98 mM); DMSO: 100 mg/mL (199.77 mM)
SMILES

CCC(O[C@]1(C(SCF)=O)[C@H](C)C[C@@H]2[C@]1(C)C[C@H](O)[C@@]3(F)[C@H]2C[C@H](F)C4=CC(C=C[C@@]43C)=O)=O
化学全称

(6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-17-(((fluoromethyl)thio)carbonyl)-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl propionate

1.Andersson O, et al. J Allergy Clin Immunol. 1999 Apr;103(4):595-600.

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